Laboratory of Integrative Tissue Biology
Exploring Molecular Mechanisms of Tissue Protection
HIGHLIGHTS
> Check out the art and science of David Goodsell
> You can now create your own: CellPAINT
> Here, I used a bunch of Goodsell’s beautiful molecules and structures, and made my own collage in Photoshop showing a phagocyte taking up debris.
HIGHLIGHTS
> Last Friday, I was appointed a Professor at FAU. Good times ahead!
AI-driven art
Playing around with deepdreamgenerator.com. Dreaming of bone…
MILESTONE IVM imaging is up and running… working like a charm!
HIGHLIGHTS
> We’re hiring!!! Find the official posting here : bit.ly/uderhardt-postdoc
HIGHLIGHTS
Just gonna leave that one here…
SHORT A combination of real volume imaging data and animation tools in Blender.
HIGHLIGHTS
> We’re hiring!!! Find the official posting here : bit.ly/uderhardt-phd
EXPLORING THE SPACE!
Blender is an open-source 3D content creation suite, and it is free of charge! At first, the GUI and general handling can be a bit intimidating, and the learning curve is quite steep, but the performance is simply impressive. Using a Cx3cr1-gfp reporter system, I visualized microglia within 200 μm brain slices trying to capture their entire dendrite morphology. Iso-surfaces were created in IMARIS, exported as .wrl, imported into blender, custom-texturized, and rendered. Hover over images to zoom.
SKETCHFAB
We are always looking for ways to better visualize and communicate the lab’s science. This is pretty cool: Sketchfab allows you to upload 3D models people can directly interact with, supposed to also have VR options… and you directly embed the model into your website. So click it, drag it, spin it, zoom in and out, and go wild with it…
DESCRIPTION Intravital microscopy allowed me to capture this individual resident tissue macrophage in the process of sending long membranous processes towards a laser-induced sterile stromal damage in order to contain it (“cloaking”). Fluorescence intensity data was rendered as an iso-surface in IMARIS, exported as .vrml, processed in MeshLab, saved as .stl, uploaded to Sketchfab, and finally ended up here. A long way for a single cell. Enjoy!